Vaccine rollout refers to the distribution and administration of vaccines across a population, exemplified dramatically during COVID-19 pandemic responses. Vaccine distribution involves multiple government levels: federal government procures vaccines and manages national supply through the Public Health Agency of Canada; provincial governments plan distribution, establish priorities, and manage provincial health systems; municipalities often operate vaccination clinics, manage local logistics, and communicate with residents. The COVID-19 rollout highlighted intergovernmental coordination challenges and successes. Municipal roles included operating mass vaccination sites, coordinating with local health units, and reaching vulnerable populations. Vaccine rollout logistics include cold chain management, appointment systems, recordkeeping, and equity considerations ensuring access across communities.